Inhibition of endothelial miR-24 significantly reduced myocardial infarct size via prevention of endothelial apoptosis and enhancement of vascularity after AMI through targeting of the endothelium-enriched transcription factor GATA2 and the p21-activated kinase 4 (PAK4), which led to preserved cardiac function and was closely related to HF [82]. The gene discussed is PAK4; the disease is hydrops fetalis.