NFKB1 and progressive multifocal leukoencephalopathy: In our patients, mutations in NFKB1 and STAT3 also led to opportunistic infections, including Mycobacterium avium intracellulare, JC virus-induced progressive multifocal leukoencephalopathy, Pneumocystis jirovecii pneumonia, and Molluscum contagiosum.