This study also showed that C57Bl6/KaLwRijHsd mice, which are permissive to 5T murine myeloma cells, have significantly lower adiponectin gene expression and adiponectin protein in their BM and lower total serum adiponectin compared to the non-permissive, but closely related C57BL6/J mice (110). The gene discussed is ADIPOQ; the disease is plasma cell myeloma.