We next highlighted the ways in which BMAT may support MM, for example, through bioactive lipids (as a fuel source, signaling molecule, and a substrate for lipid peroxidation), and myeloma-supportive adipokines (e.g., IL-6, TNFα, MCP-1, PAI-1, IL-6, resistin, and leptin). Here, TNF is linked to plasma cell myeloma.