Relative expression of AD-relevant miRNAs in the prion diseases sJCD and Gerstmann-Straussler-Scheinker (GSS) indicate a similar up-regulation of these inducible, NF-kB-regulated miRNAs; clinical parameters including age and gender of these human PrD cases (both JCD and GSS) have been described in detail elsewhere (Lukiw et al., 2011). The gene discussed is NFKB1; the disease is Alzheimer disease.