A recent study quantifying T1ρ in the medial temporal lobe (MTL) showed increased T1ρ in MTL WM and GM in AD (Haris et al., 2011) and that its measurement, like DTI, surpassed the sensitivity of CSF biomarkers Tau and Aβ42 in diagnosing AD, though CSF biomarkers showed better specificity (Haris et al., 2015). This evidence concerns the gene MAPT and Alzheimer disease.