CCN2 and liver cancer: It has been reported (Qi et al, 2015) that the addition of netrin‐1 to the culture medium of human liver cancer, glioblastoma, and embryonic kidney cell lines induces the expression of the Yes‐associated protein (YAP), of TAZ, a transcriptional coactivator with a PDZ‐binding motif (WWTR1), and of the connective tissue growth factor (CTGF), the transcription of which is initiated by YAP/TAZ.