There were 8 overlapping pathways between the LUV and HUV samples at 12 h in the top 10 altered pathways; these included the Cell Cycle, Mitotic Metaphase and Anaphase, Mitotic Prometaphase, APC-C mediated degradation of cell cycle proteins, Kinesin, Cell Cycle Checkpoints, RB in cancer, and Gastric cancer network 1. Here, RB1 is linked to cancer.