Lack of association between allergen type in skin allergen-testing and the plasma levels of LRG1 and TGFBR2 in the AR and AS patient population, and 3 different allergens caused similar pattern of reduced LRG1 and TGFBR2 concentrations in plasma, we believe that reduction of plasma levels of LRG1 and TGFBR2 is a common feature of allergy regardless of allergen type. The gene discussed is TGFBR2; the disease is Allergy.