SH3D19 and infection: Considering the phylogenetic distribution of mAAV-EVE1 among diprotodontians, we infer that infection, endogenisation, and genetic fixation of the exogenous marsupial AAV sequence that became mAAV-EVE1 occurred within a stem macropodoid population sometime after the Phalangeroidea-Macropodoidea split (45.3 MYA), but prior to the macropodoid radiation (27 MYA).