In order to elucidate whether fibroblasts might be responsible for the miRNA expression in SSc-ILD we stimulated healthy lung fibroblasts (n = 6) and fibroblasts from the lungs of patients with SSc-ILD (n = 6) with cytokines known to be involved in the progression of lung disease: TGFβ, IL-13, and IFN [6]. This evidence concerns the gene TGFB1 and systemic sclerosis.