RUNX2 and cancer: MiR-203 has been shown to regulate the biological function of cancer cells, including cell proliferation, migration, invasion and chemoresistance, by targeting several target genes, such as CKAP2, LASP1, BIRC5, WASF1, ASAP1, SNAI2, and RUNX2 in prostate cancer15, 27 and AKT2 in CRC22.