In this regard, CC chemokine receptor 3 (CCR3) is selectively expressed by eosinophils, basophils, and a part of TH2 cells that play major roles in allergic diseases (Daugherty et al., 1996; Kitaura et al., 1996; Sallusto et al., 1997; Uguccioni et al., 1997). Here, CCR3 is linked to allergic disease.