CCL17 and atopic eczema: Furthermore, we and others have demonstrated that the serum levels of CCL17 and CCL22 substantially increase in patients with allergic diseases (Kakinuma et al., 2001, 2002; Fujisawa et al., 2002; Horikawa et al., 2002) and that the serum levels of CCL17 correlate particularly with the disease activities of atopic dermatitis (Kataoka, 2014).