MAP2K7 and cancer: As of 2016, many clinical trials are ongoing with several MEK inhibitors demonstrating the endeavor to cure cancers and rasopathies (for example: selumetinib/AZD6244; MEK162; Refametinib/BAY86-9766; Trametinib/ GSK1120212; GDC-0973; PD-0325901; RO5126766 and Cobimetinib/GDC-0973).