THPO and autoimmune thrombocytopenic purpura: Testing on ITP patients demonstrated consistent IPF elevations, typically >10%, with normal or near normal results in patients with marrow suppression.4 Borderline elevations may occur with liver cirrhosis, presumably due to the mixed etiology of low platelet count in these cases involving both increased platelet production and decreased hepatic thrombopoietin production.6 Present study was done to observe the importance of immature platelet fraction for the diagnosis of ITP in patients.