ACHE and Alzheimer disease: Further to their MAO/ChE inhibitory properties, ASS234 and M30D exert beneficial pharmacological effects in therapy of AD by inhibiting Aβ plaque formation and aggregation and, by blocking AChE-mediated Aβ1-40/Aβ1-42 aggregation (Kupershmidt et al., 2012; Bolea et al., 2013).