MiR-145 and miR-143 located in 5q33.1 inhibit NSCLC cell growth and metastasis by targeting epidermal growth factor receptor (EGFR) and nucleoside diphosphate linked moiety X-type motif 1 (NUDT1) or LIM domain kinase 1 (Limk1) [23, 24]. The gene discussed is NUDT1; the disease is non-small cell lung carcinoma.