EGFR and triple-negative breast carcinoma: In conclusion, we demonstrate here that EGFR and ROCK are potential in vivo targets for triple-negative breast cancer in a combination setting: co-inhibition of EGFR and ROCK has a profound inhibitory impact on cell proliferation in a panel of TNBC cell lines, in vitro as well as in mice, which was at least partially explained by the induction of cell cycle arrest.