As seen in Figure 3G, Ki-67 staining in aggressive S2B11 and S2G7 clones were significantly higher compared to non-aggressive S2D10 and S2F10 clones, indicating that the S2B11 and S2G7 populations undergo rapid cell proliferation, which would be advantageous for tumor initiation and progression. Here, MKI67 is linked to neoplasm.