NFE2L2 and amyotrophic lateral sclerosis: In a published study, the association between different NFE2L2 SNPs and human cancers was established 24; however, there were also several studies that did not find the association between NFE2L2 polymorphisms and the risk of Alzheimer's 25, Parkinson's diseases 26 or oxidative stress biomarkers in patients with amyotrophic lateral sclerosis 27.