ANGPT1 and acute kidney injury: Specifically, every standard deviation higher concentration of Ang-1 was associated with an estimated 50 % lower adjusted risk of stage 2–3 AKI (95 % CI: 33 % lower to 67 % lower, p = 0.002; Additional file 2) and every standard deviation higher concentration of Ang-2 was associated with an estimated 59 % higher risk of stage 2–3 AKI (95 % CI: 48 % higher to 72 % higher, p < 0.001; Additional file 2).