Patients with higher stages of AKI had higher median concentrations of the inflammatory biomarkers IL-6, IL-8, IL-17, G-CSF, and TNFR-1, higher median concentrations of the endothelial biomarkers Ang-2, the Ang-2/Ang-1 ratio, and sVCAM-1, and lower median concentrations of Ang-1 (Table 2, Fig. 1). This evidence concerns the gene TNFRSF1A and acute kidney injury.