In addition, compared with WT, C5aR1-/- kidneys had a lower Ly6Chi population and reduced ratios of Ly6Chi to Ly6Clo populations within the MO/MΦs (Ly6G-CD11b+) compartment at both day 2 and day 14 after infection (Figure 3a, d, and e). This evidence concerns the gene ITGAM and infection.