2001; Basile 2007; Kramann et al. 2014). For example, VEGF, an important growth factor, is produced in the kidney proximal tubule. In many models of renal disease, VEGF expression is decreased in the proximal tubule. Exogenous VEGF administered to preserve renal capillaries has a therapeutic window only in the early postinjury period (Dusso et al. 2005; Ascon et al. 2008, 2009). Here, VEGFA is linked to kidney disorder.