Importantly, this study was the first to identify 14 methylated genes in oligodendroglial tumor patients, namely APC, MLH1, ATM, RARB, HIC1, BRCA1, CASP8, BRCA2, CD44, VHL, FHIT, IGSF4, CDH13, and MLH1. The gene discussed is RARB; the disease is oligodendroglial tumor.