TGFβ induces cadherin-11 expression in lung adenocarcinoma cells and this upregulation is required for the EMT response, while on the other hand, mice with a homozygous loss of cadherin-11 present with a relative resistance to pulmonary fibrosis and reduced levels of TGFβ in the lung [45]. Here, CDH11 is linked to lung adenocarcinoma.