Accordingly, TGFβ signaling, via crosstalk with oncogenic Ras and transcriptional input from the AP-1 complex, induces expression of the transcriptional repressor B lymphocyte-induced maturation protein (Blimp-1), also known as positive regulatory domain zinc finger protein 1 (PRMD1) in breast cancer cells [194]. This evidence concerns the gene TGFB1 and breast cancer.