ESR1 and breast cancer: The objective of this study was to utilize molecular docking to explore possible small molecule inhibitors from Artocarpus, examine their binding efficiencies to the ligand-binding domain of the hERα and preliminarily test for the in vitro anti-breast cancer relevance of the best glide scorer among the investigated phytomolecules in halting undue proliferation of an estrogen receptor positive breast cancer cell line.