BCL2 and breast cancer: Our results showed that the expression of E-cadherin is significantly reduced in CPS-treated cells, respect to untreated BC cells, whereas vimentin, α5 and β1 integrin subunits, ILK and Bcl-2 are upregulated (Figure 4D), indicating the occurrence of EMT and the acquisition of a more aggressive phenotype in CPS-resistant BC cells.