As shown in Figure 2A, 2B, when IKKα and IKKβ were co-overexpressed, the tumor weight increased significantly compared to the control, IKKα, IKKβ, IKKβ+IKKγ, IKKα+IKKγ, IKKα+IKKβ+IKKγ overexpression group (1.52±0.32 gram vs 0.75±0.15 gram, 0.66±0.12 gram, 0.68±0.07 gram, 0.72±0.16 gram, 0.69±0.12 gram, 0.74±0.18 gram, p<0.01, respectively). This evidence concerns the gene IKBKB and neoplasm.