However, transplantation of Sr-a1−/− bone marrow into Sr-a1+/+ mice accelerated glioma progression compared with Sr-a1+/+ to Sr-a1+/+ transplantation (Sr-a1−/− to Sr-a1+/+: 68.9 ± 42.2 mm3). The gene discussed is SRA1; the disease is central nervous system cancer.