AVP and systemic inflammatory response syndrome: The median copeptin concentrations were 70.1 pmol/L (range 2.95–500.1) in the gastrointestinal bleeding group, 5.2 pmol/L (1.25–117.8) in the SIRS group, 34.2 pmol/L (7.9–220.1) in the sepsis group, 61.8 pmol/L (2.5–527.7) in the severe sepsis group, and 128.7 pmol/L (12.0–425.0) in the septic shock group (Figure 1).