In a previous study, preformed by array-Comparative Genomic Hybridization (aCGH), we observed many genomic alterations in 22 patients and described for the first time in literature the recurrent amplification of RTEL1 (Regulator of Telomere Length 1) gene, located on 20q13.33 (OMIM: 608833), and ABCA13 (ATP-Binding Cassette, Sub-Family A, Member 13) gene, located on 7p12.3 (OMIM: 607807), in gastric adenocarcinoma, with a frequency of 50 and 23 %, respectively [11]. The gene discussed is RTEL1; the disease is gastric adenocarcinoma.