However, MEFV gene mutations are also frequently found in other AIDs, including Behcet’s disease, Henoch-Schönlein purpura, polyarteritis nodosa, ulcerative colitis, multiple sclerosis, etc. The knowladge about its role in the pathogenesis of these diseases is still obscure, but it is hypothesized that MEFV mutations could predispose to proinflammatory states [7–11]. This evidence concerns the gene MEFV and multiple sclerosis.