The two most abundant E. coli methyl-accepting chemotaxis proteins, Tsr (l-serine) and Tar (aspartate/maltose), were previously identified as the main chemoreceptors responsible for mediating taxis of UPEC strain CFT073 toward urine (85), and deletion of chemotaxis protein CheW was found to attenuate UPEC in a murine model of UTI (16). This evidence concerns the gene RBM8A and bacterial urinary tract infection.