GBP4 and infection: Gbp4 seems to be required for neutrophil homeostasis and although this observation deserves further investigation, the critical role of Gbp4 in the control of ST infection is independent of this effect, since (i) forced expression of WT Gbp4 did not affect neutrophil numbers, while increasing inflammasome-dependent infection resistance, (ii) Gcsfa overexpression failed to reverse the high susceptibility of Gbp4-deficient larvae to ST and (iii) fish overexpressing WT Gbp4 in neutrophils showed high resistance to ST infection.