This result, although unexpected and difficult to explain, was confirmed by (i) inhibition of COX2 with meloxicam; (ii) inhibition of PLA2 with ACA and CAY10502 at 24 hpi to allow neutrophil recruitment and, therefore, leave intact LTB4-dependent neutrophil recruitment; (iii) the ability of PGD2 to reverse the susceptibility of Gbp4-deficient animal, but not of their WT siblings; and (iv) the ability of AA to increase the resistance to infection of both WT and Gbp4-deficient larvae when added at the infection time but only to increase resistance of Gbp4-deficient larvae when added 24 hpi. Here, PTGS2 is linked to infection.