Despite the promising in vitro effects, DFO unexpectedly had the trend toward increasing the incidence of AngII-induced AAA (0% vs. 75% vs. 85%, p = 0.69) and the external diameter of the aorta (0.67 ± 0.11 vs. 1.62 ± 0.83 vs. 1.98 ± 1.07 mm, p-values: saline vs. AngII, p < 0.05; Saline vs. AngII + DFO, p < 0.05; and AngII vs. AngII + DFO, n.s., Supplementary Figure 2A,B). This evidence concerns the gene AGT and triple-A syndrome.