Many of these 30 genes, including CCNA2 (Cyclin-A2), MTA1 (Metastasis Associated 1), and PAK4 (P21 Protein (Cdc42/Rac)-Activated Kinase 4), were previously reported to be associated with tumor metastasis and progression in various cancers [13–15]. The gene discussed is PAK4; the disease is cancer.