Garattini et al.'s recent analysis of nuclear receptor superfamily expression in The Cancer Genome Atlas (TCGA) breast cancer RNAseq data shows that total ESRRB expression (referred to in the manuscript as NR3B2) is significantly reduced in breast tumors vs. normal breast tissue, with lowest expression in the Luminal B and Basal-Like molecular subtypes [90]. The gene discussed is ESRRB; the disease is breast carcinoma.