[36–39] We used qRT-PCR to examine whether these candidate miR-34 targets were differentially expressed in IPF type II AECs, finding that E2F1, c-Myc, and CCNE2 were significantly lower in IPF type II AECs (Fig 6A, 6B, 6C, 6D, 6E and 6F). This evidence concerns the gene E2F1 and idiopathic pulmonary fibrosis.