SEPTIN6 and Familial prostate cancer: Similarly, Li et al. (2011) [24] shown that miR-223 was able to stimulate non-metastatic gastric cancer cells to invade by targeting a tumor suppressor gene named EPB41L3. Wei et al. (2014) [31] also found accelerated invasive ability of Prostate Cancer cell lines when miR-223-3p were artificially added to the cells, but in this case through SEPT6 targeting.