The PLIN1 mRNA levels were significantly reduced in tumors with a shallow deletion of PLIN1 compared to those without such changes, including low-grade glioma, breast cancer, cervical squamous cell carcinoma, liver hepatocellular carcinoma, lung adenocarcinoma, lung squamous cell carcinoma, pancreatic adenocarcinoma and sarcoma (p < 0.05, Supplementary Figure 4B and Table 2). The gene discussed is PLIN1; the disease is central nervous system cancer.