A similar trend was maintained in basal-like, Her2-enriched and luminal B breast cancers (PBasal = 6.56 × 10−53 to 1.96 × 10−38, PHer2 = 5.48 × 10−54 to 4.37 × 10−27, PLumB = 1.34 × 10−106 to 1.81 × 10−78; Fishers exact test; Fig. 4b; Additional file 1 and Additional file 2: Table S16), in line with previous studies demonstrating a link between MYC co-amplification and these genes as well as association with poor prognosis [36, 37]. This evidence concerns the gene ERBB2 and breast cancer.