Tumours with 1.5-fold higher expression of ACSS1 or ACSS2 or both than that of adjacent normal control tissue are grouped into ACSS high-expression tumours (tumour/normal ≥1.5, n=26), while ACSS low-expression tumours (tumour/normal <1.5, n=27) express both ACSS proteins at 1.5-fold lower than its normal control (Fig. 6b). Here, ACSS2 is linked to neoplasm.