Increased levels of GSK3β phosphorylation, β‐catenin, and cMyc expression in all cystic kidney samples demonstrate that activation of the Wnt/β‐catenin signaling pathway is another common feature of human ADPKD and Pkd1 cKO mice (Fig. 5D). The gene discussed is GSK3B; the disease is autosomal dominant polycystic kidney disease.