A 34-year-old former intravenous drug user, with HCV chronic infection, psoriasis vulgaris and psoriatic arthritis was diagnosed in December 2014 with HIV infection stage B3 (CD4 cell count 93 cells/cmm) and started on combined antiretroviral therapy (cART)/DRV/r + 3TC + ABC. Here, CD4 is linked to HIV infectious disease.