To test whether the HSF1 trimers that form upon treatment with PEITC are able to enhance transcription through heat shock elements (HSEs), we used the cervical cancer HeLa HSE-luciferase reporter cell line (HeLa-HSE-luc) stably transfected with the HSP70.1 promoter fused to the luciferase gene (26). The gene discussed is HSF1; the disease is cervical carcinoma.