Herein, TGF-β, a cytokine exerting its tumor-suppressive role by inducing cell-cycle arrest and apoptosis33, was found to be significantly enhanced by LNT in tumor tissues in contrast to the positive (Cytoxan) and negative (tumor) controls (Fig. 2D), which was further confirmed by the enhancement of TAK1 expression (Fig. 2E). The gene discussed is TGFB1; the disease is neoplasm.