RSAD2 and influenza: The addition of Tnfa before or in combination with SVCV did not alter the transcript levels of the genes encoding major antiviral effectors, such as myxovirus (influenza) resistance b (Mxb), radical S-adenosyl methionine domain containing 2 (Rsad2), Mxc and protein kinase containing Z-DNA binding domains (Pkz) compared to untreated cells (Fig 4B and 4C and S2A and S2B Fig).