Besides β-catenin co-factors, TCF4 and LEF1, two other WNT/β-catenin pathway components, FXD7 and WNT10B were selected as in the microarray analysis of melanoma transcriptomes, their expression in DMBC cell populations was found to be sensitive to small changes in the microenvironment.27 Two inhibitors of WNT/β-catenin pathway, DKK1 and AXIN2, were also included. Here, AXIN2 is linked to melanoma.