Compared with the paracarcinoma tissue, the expression of LINC00052 was lower in HCC tissue (Figure 2A), and compared with the normal liver cell line LO2, LINC00052 were down-expressed in the five HCC cell lines: SMMC7721, SK-Hep1, Hu7, HepG2 and AD38 (Figure 2B). Here, LINC00052 is linked to hepatocellular carcinoma.