PREX1 and breast carcinoma: In order to determine if potential associations between P-Rex1 and MMP10 exist in human breast cancer, we first performed a comparative analysis of PREX1 and MMP10 expression in paired breast carcinomas and normal tissue, using the TCGA (The Cancer Genome Atlas) breast cancer data obtained from the UCSC Xena resource (http://xena.ucsc.edu/).