Moreover, the strong association of other autoimmune diseases with LADA, such as AITD or autoimmune Addison’s disease[32], suggests that they share a common underlying mechanism, which might be similar to that described involving the function of GPLD1 in GPI-anchor hydrolysis and the release of GPI-anchored proteins leading to the development of autoantibodies. Here, GPLD1 is linked to chronic primary adrenal insufficiency.